“A comparative study of Ultrasound guided Supraclavicular brachial plexus block using Bupivacaine alone and the combination of Bupivacaine and Buprenorphine in patients undergoing elective upper limb orthopaedic surgeries. â€
Overview
- Phase
- Phase 3 4
- Status
- Not yet recruiting
- Sponsor
- Zohra Fatima
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Onset of action is faster and duration of action is prolonged when Combination of Bupivacaine and Buprenorphine is used compared to Bupivacaine alone
Overview
Brief Summary
For ultrasound guided supraclavicular brachial plexus block, one group
received bupivacaine alone anad other group received bupivacaine and
buprenorphine. On comparing the two groups, it was found out that,
Onset of sensory blockade was similar in both the groups.
Onset of motor blockade was found to be earlier in bupivacaine alone
group.
Duration of analgesia was significantly prolonged in group that
received buprenorphine compared to bupivacaine alone.
The need for rescue analgesic is significantly delayed in the group that
received buprenorphine compared to bupivacaine alone.
There was no significant difference in the hemodynamic parameters in
both the groups.
There was no opioid related side effects in both the groups.
No other complications were seen in both the groups.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant Blinded
Eligibility Criteria
- Ages
- 20.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Assessed patients of ASA I and II status.
- •Both gender.
- •Normal biochemical and hematological parameters.
- •Age group between 20 -60years
- •Patients weighing 50-70 Kgs.
- •Mallampati score of I and II
- •No known neurological deficit
- •No local sepsis.
Exclusion Criteria
- •Patients who have not given consent.
- •Patients with anticipated difficult airway.
- •Neurological disorders
- •History of cardiovascular and respiratory disorders
- •Local bony deformities
- •History of bleeding disorders
- •Extremely obese patients.
Outcomes
Primary Outcomes
Onset of action is faster and duration of action is prolonged when Combination of Bupivacaine and Buprenorphine is used compared to Bupivacaine alone
Time Frame: 6 to 7 hours
Secondary Outcomes
- Post operative analgesia is prolonged when combination of Bupivacaine and Buprenorphine are used(2to 3 hours)
Investigators
ZOHRA FATIMA
Gulbarga institute of medical sciences