A Study on Brain Activity During Transcranial Direct Current Stimulation for Improving Finger-Hand Function in Stroke Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Changes in cortical activity using fNIRS signals during brain stimulation
研究概览
简要总结
The purpose of this study is to identify the characteristics of neural plasticity seen in stroke patients by measuring the changes in brain activity during stimulation using functional near-infrared spectroscopy (fNIRS) when applying transcranial direct current stimulation (tDCS) for the purpose of enhancing finger function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Unilateral stroke patients
- •Chronic patients over 6 months after onset
- •Subcortical stroke
- •Patients with the movement of fingers
排除标准
- •History of psychiatric disease
- •Significant other neurological diseases except for stroke
- •Difficult to perform this experiment
- •Patients with metal implants
- •History of epilepsy
- •Pregnancy
- •Skin defect at the site of electrode attachment
研究组 & 干预措施
tDCS stimulation group
Patients receive four sessions of tDCS stimulation over C3 (patient with left-sided lesion) or C4 (patient with right-sided lesion) based on 10-20 system.
干预措施: Transcranial direct current simulation (Device)
结局指标
主要结局
Changes in cortical activity using fNIRS signals during brain stimulation
时间窗: Baseline and about 10 days (immediately after brain stimulation sessions)
Cortical activities before and after brain stimulation sessions are compared.
次要结局
- Fugl-Meyer Assessment(Baseline and about 10 days (immediately after brain stimulation sessions))
- Box & Block test(Baseline and about 10 days (immediately after brain stimulation sessions))
- 9-hole pegboard test(Baseline and about 10 days (immediately after brain stimulation sessions))
- Changes in motor evoked potential(Baseline and about 10 days (immediately after brain stimulation sessions))
- Grip & Tip pinch strength test(Baseline and about 10 days (immediately after brain stimulation sessions))
- Finger tapping test(Baseline and about 10 days (immediately after brain stimulation sessions))