A Study on Brain Activity During Transcranial Direct Current Stimulation for Improving Finger-Hand Function in Stroke Patients

Samsung Medical Center1 site in 1 country30 target enrollmentSeptember 15, 2020

ConditionsStroke

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Stroke
Sponsor: Samsung Medical Center
Enrollment: 30
Locations: 1
Primary Endpoint: Changes in cortical activity using fNIRS signals during brain stimulation
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to identify the characteristics of neural plasticity seen in stroke patients by measuring the changes in brain activity during stimulation using functional near-infrared spectroscopy (fNIRS) when applying transcranial direct current stimulation (tDCS) for the purpose of enhancing finger function.

Registry

clinicaltrials.gov

Start Date

September 15, 2020

End Date

December 10, 2020

Last Updated

5 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Samsung Medical Center

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Unilateral stroke patients
•Chronic patients over 6 months after onset
•Subcortical stroke
•Patients with the movement of fingers

Exclusion Criteria

•History of psychiatric disease
•Significant other neurological diseases except for stroke
•Difficult to perform this experiment
•Patients with metal implants
•History of epilepsy
•Pregnancy
•Skin defect at the site of electrode attachment

Outcomes

Primary Outcomes

Changes in cortical activity using fNIRS signals during brain stimulation

Time Frame: Baseline and about 10 days (immediately after brain stimulation sessions)

Cortical activities before and after brain stimulation sessions are compared.

Secondary Outcomes

9-hole pegboard test(Baseline and about 10 days (immediately after brain stimulation sessions))
Fugl-Meyer Assessment(Baseline and about 10 days (immediately after brain stimulation sessions))
Changes in motor evoked potential(Baseline and about 10 days (immediately after brain stimulation sessions))
Grip & Tip pinch strength test(Baseline and about 10 days (immediately after brain stimulation sessions))
Box & Block test(Baseline and about 10 days (immediately after brain stimulation sessions))
Finger tapping test(Baseline and about 10 days (immediately after brain stimulation sessions))