Predictive Factors of Response to Somatostatin Analogues in Acromegalic Patients With Persistent Disease Following Surgery
- Conditions
- Acromegaly
- Registration Number
- NCT00500227
- Lead Sponsor
- Ipsen
- Brief Summary
The objective of this study is to evaluate, in acromegalic patients with disease persistence after surgery who are treated with somatostatin analogues, the histopathological, clinical, morphological and biochemical factors which are predictive of hormonal control.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 55
- Acromegalic patients with persistent disease (growth hormone ≥ 1ng/ml following oral glucose tolerance test and/or insulin like growth factor 1 above the normal range for sex and age) 3 to 6 months after transsphenoidal or transfrontal surgery
- Patients not contributing enough material for a tumour histopathological study
- Patients who have received radiation therapy or will receive it during the observational study period
- Patients who are being treated, or in whom treatment is anticipated, with either a dopaminergic agonist or a growth hormone receptor antagonist
- Patients with a history of hypersensitivity to somatostatin analogues
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (30)
Hospital "Juan Canalejo"
🇪🇸A Coruña, Spain
Hospital General Universitari d'Alacant
🇪🇸Alicante, Spain
Hospital de Cruces
🇪🇸Barakaldo, Spain
Hospital de la Santa Creu i Sant Pau
🇪🇸Barcelona, Spain
Hospital General de la Vall d´Hebron
🇪🇸Barcelona, Spain
Hospital Clínic i Provincial de Barcelona
🇪🇸Barcelona, Spain
Hospital "Mútua de Terrassa"
🇪🇸Barcelona, Spain
Hospital Prínceps d'Espanya
🇪🇸Barcelona, Spain
Hospital Universitario de Getafe
🇪🇸Getafe, Spain
Complejo Hospitalario de León. Hospital Virgen Blanca.
🇪🇸Leon, Spain
Scroll for more (20 remaining)Hospital "Juan Canalejo"🇪🇸A Coruña, Spain