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Clinical Trials/NCT02976311
NCT02976311
Completed
Not Applicable

Comparison of Inflammatory Reactions Following Two Different Cesarean Surgery Techniques; The Modified Misgav-Ladach Versus the Pfannenstiel-Kerr Technique

Kayseri Education and Research Hospital0 sites88 target enrollmentApril 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Delivery
Sponsor
Kayseri Education and Research Hospital
Enrollment
88
Primary Endpoint
TNF-alpha
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

In this study, the investigators aimed to find out whether there are any differences in inflammatory reactions occured subsequent to two different cesarean delivery techniques; modified Misgav-Ladach vs Pfannenstiel-Kerr techniques.

Detailed Description

Cesarean section is one of the most undertaken operations in women of childbearing age. However, there is not a unique cesarean surgery technique. Pfannenstiel , reported his own technique in 1897. Because of the applicability of the technique, it went down well among obstetricians. After three decades, Kerr evolved this technique, and Pfannenstiel-Kerr technique became the method of choice until late 70's. In 1972, Stark et al defined the Misgav Ladach technique and in the following years this technique became popular among obstetricians. In late 80's Misgav Ladach technique was modified and started to be more popular. But, still Pfannenstiel-Kerr technique continued to be used frequently and studies comparing clinical outcomes of these two techniques were conducted for several times. However, the inflammatory responses which occured subsequent to application of these techniques were not investigated. This is the first study investigating the inflammatory response emerged after different cesarean surgery techniques.

Registry
clinicaltrials.gov
Start Date
April 2016
End Date
September 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Kayseri Education and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

Hatice Akkaya

doctor

Kayseri Education and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • Cesarean section for the first time
  • Term,singleton pregnancy

Exclusion Criteria

  • Any inflammatory disease
  • Any pregnancy complication; IUGR,preeclampsia,preterm labor,preterm premature rupture of membranes
  • Pregnancies \<37weeks gestational age

Outcomes

Primary Outcomes

TNF-alpha

Time Frame: 24 hours

percentage of difference in serum IL-6 levels just before the beginning of the surgery and at the 24th hour of the surgery

IL-6

Time Frame: 24 hours

percentage of difference in serum IL-6 levels just before the beginning of the surgery and at the 24th hour of the surgery

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