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临床试验/NCT02976311
NCT02976311已完成不适用

Comparison of Inflammatory Reactions Following Two Different Cesarean Surgery Techniques; The Modified Misgav-Ladach Versus the Pfannenstiel-Kerr Technique

Kayseri Education and Research Hospital0 个研究点目标入组 88 人开始时间: 2016年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
88
主要终点
TNF-alpha

研究概览

简要总结

In this study, the investigators aimed to find out whether there are any differences in inflammatory reactions occured subsequent to two different cesarean delivery techniques; modified Misgav-Ladach vs Pfannenstiel-Kerr techniques.

详细描述

Cesarean section is one of the most undertaken operations in women of childbearing age. However, there is not a unique cesarean surgery technique. Pfannenstiel , reported his own technique in 1897. Because of the applicability of the technique, it went down well among obstetricians. After three decades, Kerr evolved this technique, and Pfannenstiel-Kerr technique became the method of choice until late 70's. In 1972, Stark et al defined the Misgav Ladach technique and in the following years this technique became popular among obstetricians. In late 80's Misgav Ladach technique was modified and started to be more popular. But, still Pfannenstiel-Kerr technique continued to be used frequently and studies comparing clinical outcomes of these two techniques were conducted for several times. However, the inflammatory responses which occured subsequent to application of these techniques were not investigated. This is the first study investigating the inflammatory response emerged after different cesarean surgery techniques.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
Single (Investigator)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Cesarean section for the first time
  • Term,singleton pregnancy

排除标准

  • Any inflammatory disease
  • Any pregnancy complication; IUGR,preeclampsia,preterm labor,preterm premature rupture of membranes
  • Pregnancies <37weeks gestational age

结局指标

主要结局

TNF-alpha

时间窗: 24 hours

percentage of difference in serum IL-6 levels just before the beginning of the surgery and at the 24th hour of the surgery

IL-6

时间窗: 24 hours

percentage of difference in serum IL-6 levels just before the beginning of the surgery and at the 24th hour of the surgery

次要结局

未报告次要终点

研究者

发起方
Kayseri Education and Research Hospital
申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Hatice Akkaya

doctor

Kayseri Education and Research Hospital

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