Comparison of Inflammatory Reactions Following Two Different Cesarean Surgery Techniques; The Modified Misgav-Ladach Versus the Pfannenstiel-Kerr Technique
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 88
- 主要终点
- TNF-alpha
研究概览
简要总结
In this study, the investigators aimed to find out whether there are any differences in inflammatory reactions occured subsequent to two different cesarean delivery techniques; modified Misgav-Ladach vs Pfannenstiel-Kerr techniques.
详细描述
Cesarean section is one of the most undertaken operations in women of childbearing age. However, there is not a unique cesarean surgery technique. Pfannenstiel , reported his own technique in 1897. Because of the applicability of the technique, it went down well among obstetricians. After three decades, Kerr evolved this technique, and Pfannenstiel-Kerr technique became the method of choice until late 70's. In 1972, Stark et al defined the Misgav Ladach technique and in the following years this technique became popular among obstetricians. In late 80's Misgav Ladach technique was modified and started to be more popular. But, still Pfannenstiel-Kerr technique continued to be used frequently and studies comparing clinical outcomes of these two techniques were conducted for several times. However, the inflammatory responses which occured subsequent to application of these techniques were not investigated. This is the first study investigating the inflammatory response emerged after different cesarean surgery techniques.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 35 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Cesarean section for the first time
- •Term,singleton pregnancy
排除标准
- •Any inflammatory disease
- •Any pregnancy complication; IUGR,preeclampsia,preterm labor,preterm premature rupture of membranes
- •Pregnancies <37weeks gestational age
结局指标
主要结局
TNF-alpha
时间窗: 24 hours
percentage of difference in serum IL-6 levels just before the beginning of the surgery and at the 24th hour of the surgery
IL-6
时间窗: 24 hours
percentage of difference in serum IL-6 levels just before the beginning of the surgery and at the 24th hour of the surgery
次要结局
未报告次要终点
研究者
Hatice Akkaya
doctor
Kayseri Education and Research Hospital
