JPRN-UMIN000044562已完成未知
Clinical pathological gene research for the pathophysiology and diagnostic accuracy of pancreatic tumors - Genetic research of pancreatic tumors
niversity of Yamanashi Division of gastroenterology and hepatology0 个研究点目标入组 172 人开始时间: 2021年6月16日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 172
研究概览
简要总结
The most common genetic abnormalities obtained were KRAS (82%), TP53 (57%), SMAD4 (19%), and RET (16%). Genetic abnormalities that could be markers for FDA-approved molecular-targeted drugs were found in 30 patients (20%) in 93 locations, and 14% of patients had abnormalities in genes related to homologous recombination repair, a potential marker for FOLFIRINOX, which is used in clinical practice.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- ot applicable 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •not applicable
研究者
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