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Clinical Trials/NCT05766787
NCT05766787
Completed
Not Applicable

The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses

Alcon Research15 sites in 1 country190 target enrollmentMarch 29, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Refractive Ametropia
Sponsor
Alcon Research
Enrollment
190
Locations
15
Primary Endpoint
Least Squares Mean Distance VA With Study Lenses at Week 1
Status
Completed
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.

Detailed Description

In this crossover study, subjects will wear each lens product for approximately 14 days and attend 7 scheduled visits. The expected overall duration of exposure to the study products is approximately 28 days.

Registry
clinicaltrials.gov
Start Date
March 29, 2023
End Date
June 2, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Successful wear of spherical soft contact lenses in both eyes for a minimum of 5 days per week and 8 hours per day during the past 3 months.
  • Best Corrected Visual Acuity (BCVA) of 20/25 Snellen (0.10 logMAR) or better in each eye.
  • Willing to stop wearing habitual contact lenses for the duration of study participation.
  • Other protocol-specific inclusion criteria may apply.

Exclusion Criteria

  • Any eye infection, inflammation, abnormality or disease (including systemic) that contraindicates contact lens wear, as determined by the investigator.
  • Any use of systemic or ocular medications for which contact lens wear could be contraindicated, as determined by the investigator.
  • Habitual wear of AOHP contact lenses.
  • Habitual wear of any daily disposable contact lenses.
  • Other protocol-specified exclusion criteria may apply.

Outcomes

Primary Outcomes

Least Squares Mean Distance VA With Study Lenses at Week 1

Time Frame: Week 1 of each lens product worn during the corresponding crossover period

Visual acuity (VA) was assessed for each eye individually with study lenses in place using logarithmic of the Minimum Angle of Resolution (logMAR) reading charts. LogMAR values typically range from -0.3 (20/10 vision on the Snellen chart) to 1 (20/200 vision). A logMAR acuity of 0.0 corresponds to 20/20 Snellen acuity (normal distance visual acuity), with a negative value denoting better than 20/20 visual acuity.

Study Sites (15)

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