Observational - WT-1's Role in Leukemogenesis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- WT1 and VEGF-1 expression
研究概览
简要总结
This research study is studying biomarkers in patients with acute promyelocytic leukemia. Studying samples of bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and about biomarkers related to cancer.
详细描述
OBSERVATIONAL STUDY MODEL: Case-only TIME PERSPECTIVE: Retrospective BIOSPECIMEN RETENTION: Samples With DNA BIOSCPECIMEN DESCRIPTION: Bone marrow STUDY POPULATION DESCRIPTION: Primary Care Clinic SAMPLING METHOD: Non-Probability Sample
PRIMARY OBJECTIVES:
I. To measure WT1 and VEGF-1 expression in patients with acute promyelocytic leukemia.
OUTLINE: This is a multicenter study.
Patient mRNA samples from diagnosis are analyzed via quantitative PCR to measure WT1 and VEGF-1 expression.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of acute promyelocytic leukemia [t(15;17) translocation]
- •Not specified
- •Not specified
排除标准
- 未提供
结局指标
主要结局
WT1 and VEGF-1 expression
时间窗: Baseline
次要结局
未报告次要终点