Prevalence and Factors Associated With Sleep Disorders in Inflammatory Bowel Disease

Not Applicable

Completed

• Conditions: Ulcerative Colitis; Sleep Disorder; Inflammatory Bowel Diseases; Crohn Disease
• Interventions: Other: Ulcerative colitis Disease Activity Index

• Registration Number: NCT06439641
• Lead Sponsor: CHU de Reims

Brief Summary

Inflammatory bowel diseases (IBD) including Crohn's disease (CD) and ulcerative colitis (UC), are an inflammatory disease that can affect the entire digestive tract from the mouth to the anus for CD and the entire colon and rectum for UC. They mainly affect adolescents and young adults. These pathologies evolve in relapses interspersed with phases of remission. Sometimes associated with extraintestinal manifestations (joint, dermatological, ophthalmological or biliary systems), chronic inflammation of the digestive tract and the resulting symptoms (abdominal pain, diarrhea, rectal syndrome, etc.) lead to a significant alteration in the quality of life of patients in all spheres of activity (professional, sexual, social).

Sleep is a basic neurophysiological state, the normal total duration of which in humans is between six and ten hours per day. It is an essential element of the circadian rhythm in humans, influencing certain cellular functions and in particular the synthesis of cytokines and pro-inflammatory molecules. Sleep disturbances and disruption of the circadian rhythm lead to metabolic and immunological dysfunctions, which may be involved in chronic inflammatory conditions through changes in the immune response.

In the field of IBD, many studies suggest poor sleep quality in patients with IBD. While there seems to be a link between sleep disorders and impaired quality of life with a socio-professional impact in these patients, the links between IBD activity, its treatment and sleep disorders are poorly studied, with discordant results in previous studies.

In order to enrich our knowledge on this topic, the investigators wish to study the prevalence and risk factors associated with sleep disorders in IBD patients in order to improve patients' quality of life

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-05-28
• Study First Submitted QC: 2024-05-28
• Study First Posted: 2024-06-03
• Study Start: 2024-07-03
• Primary Completion: 2024-11-26
• Status Verified: 2025-05
• Study Completion: 2025-05-02
• Last Update Submitted: 2025-05-02
• Last Update Posted: 2025-05-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Adult patients with Crohn's disease (CD) or ulcerative colitis (UC) presenting for consultation or hospitalization in Gastroenterology unit

Exclusion Criteria

• Patients with an identified sleep pathology

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Patients with Inflammatory bowel diseases	Ulcerative colitis Disease Activity Index	patients with IBD

Primary Outcome Measures

Name	Time	Method
Pittsburgh Sleep Quality Index Questionnaire	Only one time at inclusion	Score between 0 to 12, the higher is the worse

Trial Locations

Locations (1)

Chu Reims; 🇫🇷 Reims, France