Relative Efficacy of Vitamins D2 and D3 in Adult Humans
Not Applicable
Completed
- Conditions
- Healthy
- Registration Number
- NCT01139840
- Lead Sponsor
- Creighton University
- Brief Summary
Vitamin D2 in chronic dosing will produce less of an elevation of serum 25(OH)D than will the same dose of vitamin D3.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
- willingness to withhold supplement use for duration of study
- willingness to avoid sun exposure for duration of study
Exclusion Criteria
- vitamin D supplement use
- conditions that affect vitamin D metabolism by the body
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method AUC for increment in serum 25(OH)D 12 weeks
- Secondary Outcome Measures
Name Time Method change in vitamin D content of subcutaneous fat 12 weeks
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms behind the differential efficacy of vitamin D2 and D3 in elevating serum 25(OH)D levels?
How does the relative efficacy of vitamin D2 and D3 compare to standard-of-care treatments for vitamin D deficiency in adults?
Which biomarkers are associated with response prediction to vitamin D2 versus D3 supplementation in healthy individuals?
What are the known adverse events and management strategies for chronic vitamin D2 and D3 administration in clinical practice?
Are there combination approaches or competitor drugs that enhance vitamin D2 or D3 efficacy in maintaining optimal serum 25(OH)D concentrations?
Trial Locations
- Locations (1)
Creighton University Medical Center
🇺🇸Omaha, Nebraska, United States
Creighton University Medical Center🇺🇸Omaha, Nebraska, United States