OPTAMI (Optimized Therapy of Acute Myocardial Infarction) - Registry

Completed

• Conditions: ST-Elevation Myocardial Infarction; Myocardial Infarction; Non-ST-Elevation Myocardial Infarction

• Registration Number: NCT01197729
• Lead Sponsor: Stiftung Institut fuer Herzinfarktforschung

Brief Summary

OPTAMI documents the characteristics of consecutive patients with acute STEMI and NSTEMI in hospital everyday-life in Germany, their acute and adjuvant medication treatment, events until discharge (e.g. mortality, stroke, re-MI), and their medication for secondary prevention at discharge.

In the follow up-period of one year, information is collected concerning events as mortality, stroke, re-MI, coronary interventions (PCI, CABG) and re-hospitalisation.

The implementation of guideline-adjusted therapy in hospital everyday-life is reviewed. The usefulness of the European standard for data acquisition in cardiology (CARDS = Cardiology Audit and Registration Standards) is evaluated.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-10
• Primary Completion: 2009-02
• Study Completion: 2010-02
• Study First Submitted: 2010-09-07
• Study First Submitted QC: 2010-09-07
• Study First Posted: 2010-09-09
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-18
• Last Update Posted: 2024-12-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 3248

Inclusion Criteria

• all patients admitted to hospital with an acute ST-Elevation myocardial infarction or with an acute Non-ST-Elevation myocardial infarction, both not older than 24 h

Exclusion Criteria

• missing informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Documentation of characteristics from consecutive patients with an acute STEMI or an acute NSTEMI in hospital daily routine in Germany.	10/01/2005-02/01/2009

Secondary Outcome Measures

Name	Time	Method
Documentation of acute invasive and adjuvant medical therapy of STEMI and NSTEMI in hospital daily routine in Germany	10/01/2005-02/01/2009
Documentation of hospital mortality and non-fatal cerebrovascular complications (stroke, re-myocardial infarction)	10/01/2005-02/01/2009
Documentation of the one-year mortality, the non-fatal cerebrovascular complications (stroke, re-myocardial infarction) as well as of the coronar interventions (PCI, Bypass operation) and hospital admissions during the first year post STEMI or NSTEMI	10/01/2005-02/01/2009
Documentation of medication for secondary prevention at hospital discharge	10/01/2005-02/01/2009
Verification of the benefits of the European Standards for Data Collection for Cardiology (CARDS = Cardiology Audit and Register Standards) in daily hospital routine.	10/01/2005-02/01/2009
Verification of the implementation of therapy according to the guidelines for STEMI and NSTEMI patients in daily hospital routine in Germany.	10/01/2005-02/01/2009

Trial Locations

Locations (2)

Medizinische Klinik und Poliklinik, Universitätklinikum Münster; 🇩🇪 Münster, Germany

Klinikum Nürnberg Süd / Cardiology; 🇩🇪 Nürnberg, Germany