Population Burden of Sexually Transmitted Infections and Implication for Intervention in Hong Kong
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,977
- 试验地点
- 1
- 主要终点
- effectiveness of STI intervention strategies
研究概览
简要总结
This is a 5-year cross-disciplinary sexually transmitted infection (STI) project involving a) territory-wide and community-based studies (survey and specimen collection); b) simulation of STI transmission dynamics and comparison of STI intervention strategies through mathematical modelling and cost-effectiveness analysis. The aim of this project is to assess the burden and the transmission dynamics of STIs in the general population and men who have sex with men (MSM) in Hong Kong. Around 1300 sexually experienced adults and 900 MSM would be recruited, 100 participants would be invited for individual in-depth interviews. Main outcome measures include STI history and service preference, effectiveness as measured by the proportion of new STI infections (chlamydia, gonorrhoea and human papillomavirus infections) averted above base-case scenario, and incremental cost-effectiveness ratio.
详细描述
After completion of baseline questionnaire, the participants are invitied for STI self-sampling. If agree, a package of self-sampling kits, instructions, and packaging materials for return post would be delivered to their selected collection points. The second round of self-sampling would be offered at least one year from the first round of self-sampled specimens collected.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •aged 18 or above
- •ever having sex
- •normally living in Hong Kong
- •can communicate in English or Chinese
排除标准
- •failed to provide consent
结局指标
主要结局
effectiveness of STI intervention strategies
时间窗: 10 years
incremental cost-effectiveness ratio
self-reported STI diagnosis in questionnaire
时间窗: up to 2 years
number of STI diagnosis
次要结局
- willingness to pay for STI testing reported in questionnaire(12 months)
- STI symptom reported in questionnaire(12 months)
- prevalence of STI estimated through laboratory testing(12 months)
研究者
Ngai Sze WONG
Assistant Professor
Chinese University of Hong Kong