Retrospective Study on Endoscopic Findings of Gastritis in Children Attending GIT Endoscopic Unit of Assiut University Children Hospital (AUCH) (15 Years)
试验速览
- 阶段
- 不适用
- 入组人数
- 500
- 主要终点
- causes of gastritis in children as shown by upper endoscopy
研究概览
简要总结
Gastritis defines any (histologically confirmed) inflammation of the gastric mucosa
详细描述
Gastritis is a very common disease in children. The main presentation of children with gastritis is recurrent abdominal pain and dyspepsia or vomiting. Young children may have hematemesis or melena as presentation. Drug induced or food related gastritis presents usually with acute symptoms but Helicobacter pylori gastritis have mainly recurrent abdominal pain and dyspeptic symptoms. Other presentations include diarrhea, constipation, flatulence, bloating, fatigue, low energy level, weight loss, muscle loss, bad breath etc.
The main causes of gastritis are infections, inflammation and other disorders affect the gastric mucosa in pediatric patients. Helicobacter pylori infection is the most common cause of gastritis in children which is also responsible for the majority of duodenal ulcers.
Acute erosive gastritis is most commonly the result of metabolic stress or drug or corrosive injury.
Other major causes of gastritis include celiac disease, allergic disorders, and Crohn's disease .Medication as NSAIDs, uremia, ischemia, shock, radiation, sepsis, trauma, severe burns and surgery.
Endoscopic pictures in acute gastritis may be in the form of:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 18 Years(Child, Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All children diagnosed as gastritis by upper endoscopy and bio gastric biopsy
排除标准
- •• All children underwent upper endoscopy during the study period not diagnosed as gastritis
结局指标
主要结局
causes of gastritis in children as shown by upper endoscopy
时间窗: average 1 year
* infections * inflammation * Helicobacter pylori * Acute erosive gastritis
次要结局
未报告次要终点
研究者
HM Reyad
principle investigator
Assiut University
