IMPRINT: A Pilot Study to Improve Germline Testing in At-Risk Patients With Prostate Cancer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Prostate Cancer
- Sponsor
- University of California, San Diego
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Number of Participants Agreeing to Proceed With Germline Testing Among Those Approached With the Educational Intervention.
- Status
- Completed
- Last Updated
- 3 months ago
Overview
Brief Summary
A quality improvement initiative to improve rates of germline testing among men with prostate cancer through the use of an in-clinic educational session.
Detailed Description
This is a prospective single arm quality improvement initiative for the use of a standardized educational intervention on germline testing in prostate cancer to improve the rates of germline genetic testing among patients recommended for testing. Patients who consent to the study will undergo a one-on-one education session regarding the rationale and the benefits/risks of germline testing. Following the educational session, if a patient wishes to proceed with testing, they will sign the standard consent to proceed with germline testing via a commercial assay.
Investigators
Rana Mckay
Associate Professor of Medicine and Urology
University of California, San Diego
Eligibility Criteria
Inclusion Criteria
- •Men, age greater than or equal to 18 years of age.
- •Diagnosis of prostate cancer of any histology.
- •Must meet NCCN guidelines for germline testing
Exclusion Criteria
- •Have had prior germline testing.
- •Have somatic genetic testing that is positive for a possible germline variant.
Outcomes
Primary Outcomes
Number of Participants Agreeing to Proceed With Germline Testing Among Those Approached With the Educational Intervention.
Time Frame: Within 1 year
Germline genetic testing among adult prostate cancer patients who are recommended to receive germline testing per NCCN guidelines.
Secondary Outcomes
- Patient Baseline Knowledge of Germline Testing(Baseline)
- Patient Attitudes Towards Germline Testing and Assess the Impact of an Education Interventional on Patient Perceptions of Germline Testing(Within 18 months)
- Number of Participants With Pathogenic Germline Mutations(within 18 months)
- Patient Knowledge of Germline Testing After the Educational Intervention.(within 18 months)