REassessement After Hospitalization for Sars-COV-2 Infection : Standardized Assessment of Sequelae and Comorbidities 3 to 6 Months After Hospitalization
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 119
- 试验地点
- 1
- 主要终点
- Development or worsening of a ventilatory disorder and/or chronic respiratory failure assessed by spirometry
研究概览
简要总结
Currently, the sequelae and short-term medical and psychological impact of the sars-cov-2 infection ("CoVID-19") remain poorly described. The clinical and functional sequelae that may persist after acute sars-cov-2 ("CoVID-19") infection are essential to explore, in order to ensure the best possible follow-up of patients after discharge from hospital.
详细描述
Since sars-cov-2 ("CoVID-19") is a newly defined infection, its sequelae and short-term medical and psychological impact remain poorly described.The clinical and functional sequelae that may persist after acute sars-cov-2 ("CoVID-19") infection are essential to explore, in order to ensure the best possible follow-up of patients after discharge from hospital.
Indeed, some patients may develop chronic respiratory failure, pulmonary fibrosis, or other comorbidities including cardiovascular or metabolic diseases. The psychological impact is also essential to assess. The sequelae and comorbidities of patients could also vary depending on the severity of the initial acute involvement.
Investigators propose to explore the sequelae of patients who have been hospitalized for acute sars-cov-2 infection, between 3 to 6 months after discharge from hospital, by characterizing the incidence of chronic respiratory failure and fibrosis, as well as of various comorbidities such as cardiovascular, metabolic, and psychological diseases.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient who was hospitalized within 3 to 6 months for a sars-CoV infection
排除标准
- •Absence of signed informed consent
- •pregnancy or breastfeeding
- •patient under guardianship or curatorship
结局指标
主要结局
Development or worsening of a ventilatory disorder and/or chronic respiratory failure assessed by spirometry
时间窗: 3 to 6 months after Sars coV 2 infection
次要结局
- Incidence or worsening of renal disease(3 to 6 months after Sars coV 2 infection)
- Incidence or worsening of liver disease(3 to 6 months after Sars coV 2 infection)
- Assessment of dyspnea(3 to 6 months after Sars coV 2 infection)
- Development of pulmonary fibrosis as assessed by lung CT scan(3 to 6 months after Sars coV 2 infection)
- Incidence or worsening of cardiovascular diseases(3 to 6 months after Sars coV 2 infection)
- Incidence or worsening of psychological pathology : anxiety(3 to 6 months after Sars coV 2 infection)
- Incidence or worsening of psychological pathology: post-traumatic stress(3 to 6 months after Sars coV 2 infection)
- Determination of risk factors associated with sequelae or comorbidities(3 to 6 months after Sars coV 2 infection)
- Description of pulmonary lesions as assessed by lung CT scan(3 to 6 months after Sars coV 2 infection)
- Incidence or worsening of psychological pathology: depression(3 to 6 months after Sars coV 2 infection)
- Assessment of the socioeconomic deprivation(3 to 6 months after Sars coV 2 infection)
- Development of auto-immune disorders(3 to 6 months after Sars coV 2 infection)
- Assessment of the evolution of the humoral anti-SARS-CoV-2 immunization profile(3 to 6 months after Sars coV 2 infection)
- Patients' self-reported level of physical activity(3 to 6 months after Sars coV 2 infection)
- Incidence or worsening of psychological pathology: insomnia(3 to 6 months after Sars coV 2 infection)
- Assessment of the health-related quality of life(3 to 6 months after Sars coV 2 infection)
- Assessment of the fatigue(3 to 6 months after Sars coV 2 infection)
- development or worsening of metabolic disorders: diabetes, thyroid diseases, dyslipidemia, adrenal disorders, malnutrition(3 to 6 months after Sars coV 2 infection)