Statins for improving organ outcome in transplantatio

Not Applicable

• Conditions: Organ transplantation; Surgery

• Registration Number: ISRCTN11440354
• Lead Sponsor: ewcastle upon Tyne Hospitals NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-03
• Last Update Posted: 13 May 2024
• Study Completion: 2026-06-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 2600

Inclusion Criteria

1. Within a recruiting Intensive Care Unit
2. Patients diagnosed dead using neurological criteria
3. Consent for organ donation in place, as defined by the Human Tissue Act and accompanying legislation and Codes of Practice
4. Study-specific consent from the donor family

Exclusion Criteria

1. Aged <18 years
2. Planned donation after cessation of circulation (DCD)
3. Known donor allergic hypersensitivity to simvastatin

Study & Design

• Study Type: Interventional
• Study Design: Not specified