Identification of gene variations andtheir associated phenotypic traits in Ophthalmologic diseases
- Conditions
- Health Condition 1: H353- Degeneration of macula and posterior poleHealth Condition 2: H40- GlaucomaHealth Condition 3: E113- Type 2 diabetes mellitus with ophthalmic complications
- Registration Number
- CTRI/2023/09/057518
- Lead Sponsor
- Strand Life Sciences Private Limited
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Individuals with a confirmed diagnosis of one or more of the above diseases, along with adequate supporting clinical information (age at onset, diagnostic methods, details of disease progression, underlying medical history, phenotypic characteristics and associated SOC test results)
2.Familial cases with access to affected family members is desired
3.Ability to understand the purpose of the study and willingness to sign an Informed Consent Form
4.Willingness to provide 13-23 mL of blood
5.Tear sample (if available and possible) may be collected for DR and AMD cases only
6.Willingness to be contacted in future for recording health updates.
1.Individuals with chronic uncontrolled infection
2.Individuals with any acute illness or infection
3.Pregnant and lactating women.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The outcome of the study will aid in identification of genomic alterations associated with specific phenotypic traits & subtypes yielding novel gene-disease associations which can serve as (i) early detection biomarker (ii) diagnostic/prognostic marker & (iii) novel therapeutic targets.Timepoint: At baseline
- Secondary Outcome Measures
Name Time Method ot AvailableTimepoint: Not Applicable