跳至主要内容
临床试验/CTRI/2024/05/067078
CTRI/2024/05/067078尚未招募4 期

Evaluating the efficacy of implant sealant at implant abutment interface - a microbiological study

Panineeya Mahavidyala institute of Dental sciences and research centre1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2024年5月28日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
10
试验地点
1
主要终点
measurements of colony forming microorganims Prevotella intermedia, prorphymonas gingivalis,aggregatibacter aceticomitans

研究概览

简要总结

â–ª         Dental implantology is the fastest developing technology in the practice of dentistry today which provides a natural looking appearance and has opened the door to the 21st century in dentistry.

â–ª         Implant superstructures are the superior part of a fixed or a removable prosthesis that includes the replacement teeth and associated gingival/alveolar structures.

It has been postulated that a potential microscopic gap of 55–104 μ exists at the implant-abutment interface or the implant superstructure interface.

â–ª          Oral micro-organisms have a diameter of 10 microns and can easily pass through this micro gap. This misfit may lead to microleakage of fluids and lead to bacterial growth which may cause loss of marginal bone and may lead to periimplantitis..

â–ª          Thus, this study is formulated to check how effective is the presealing done at the implant interface by measuring colony forming units (CFU) of Preprohormones Gingivalis (PG), Prevotella intermedia(PI), Aggregetibacter actinomycetemcomitans (Aa).

ROLE OF IMPLANT SEALANT IN CONTROLLING MICROLEAKAGE

•      Implant sealant provides a reliable seal and fills the hollow spaces in the implants .

•      It is a highly viscous silicon matrix which ensures a reliable sealing and prevents the ingression of organisms.

•      The principle of this material is that as the place is already occupied, there will be no nutrition for vital activity of organism to grow and develop.

â–ª         The addition of thymol ensures better Antifungal and antibacterial activity.

â–ª         The material does not get dried off, maintaining its viscosity, and preventing formation of new micro gaps.

â–ª         gaps.

â–ª         Thin silicone film effectively prevents adhesion of plaques on supporting implants. .

The leakage without sealing agent was probably due to lack of complete wall to wall adaptation between abutment and implant.

研究设计

研究类型
Interventional
分配方式
Other
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Patients volunteering to participate in the study who have opted for implants as the choice of treatment.
  • 2.Patients with good oral hygiene having missing tooth/teeth, with the adjacent teeth free from peri-apical pathology.
  • 3.Adequate bone height and bone width.
  • 4.Systemically healthy patient...

排除标准

  • â–ª Pregnant and lactating mothers.
  • â–ª Uncontrolled diabetes â–ª Immunocompromised patients.
  • â–ª Having a history of jaw irradiation.
  • â–ª Patient with poor oral hygiene maintenance.
  • â–ª Patient who doesn’t follow recall visits.

结局指标

主要结局

measurements of colony forming microorganims Prevotella intermedia, prorphymonas gingivalis,aggregatibacter aceticomitans

时间窗: Baseline,6 months

次要结局

  • N/A(N/A)

研究者

发起方
Panineeya Mahavidyala institute of Dental sciences and research centre
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr VEERENDRA NATH REDDY

Panineeya mahavidyala institute of dental sciences and research centre

研究点 (1)

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