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临床试验/JPRN-UMIN000008711
JPRN-UMIN000008711已完成未知

The influence of oral valproate on propofol metabolism - The influence of oral valproate on propofol metabolism

Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Department of Dental Anesthsiology and Special Care Dentistry0 个研究点目标入组 33 人开始时间: 2012年8月18日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
33

研究概览

简要总结

There were no significant differences in the propofol level at 5, 10, 15, and 20 min or the free propofol level at 5 min after the intravenous administration of propofol. However, the minimum BIS was significantly lower and the time until the BIS exceeded 60 was significantly longer in the poly-VPA group. In the multivariate regression analysis, belonging to the poly-VPA group was found to be independently associated with the minimum BIS value and the time until the BIS exceeded 60.

研究设计

研究类型
Observational

入排标准

年龄范围
16years-old 至 ot applicable(—)
性别
All

入选标准

  • 未提供

排除标准

  • Patients without consent of the study

研究者

发起方
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Department of Dental Anesthsiology and Special Care Dentistry

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