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临床试验/CTRI/2024/05/067561
CTRI/2024/05/067561尚未招募不适用

The association of impulsivity response inhibition and childhood adversities to self harm or suicide

Kasturba Medical college1 个研究点 分布在 1 个国家目标入组 108 人开始时间: 2024年5月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
108
试验地点
1
主要终点
Columbia-Suicide Severity Rating Scale(CSSRS)

研究概览

简要总结

This study aims to investigate the association of impulsivity, response inhibition, and childhood adversities with intentional self-harm/suicide attempts among individuals; Objectives: 1. To investigate the association of response inhibition to intentional self-harm/suicide attempts among individuals. 2. To investigate the association of impulsivity to intentional selfharm/suicide attempts among individuals. 3. To investigate the association of childhood adversities to intentional self-harm/suicide attempts. 4. To investigate the Mediating role of response inhibition, childhood adversities, and impulsivity to self-harm/suicide attempt. Phase 1 includes approvals from the Department scientific committee (obtained), Institution Ethics Committee, and CTRI registration. The necessary scales have been translated to kannada as per WHO guidelines.Phase 2 involves recruiting patients meeting inclusion criteria from the psychiatry departments at KMC and consultation liaison psychiatry at KH. Informed consent will be obtained with translated information sheets. Sociodemographic data will be collected, followed by administering the HMSE,CSSRS,BIS-11,ACE questionnaire, and Stop signal task via laptop/computer with the psytoolkit software. The estimated time for each assessment is: sociodemographic proforma(15 mins),HMSE(15mins),CSSRS(20 mins),BIS 11(15 mins), Stop signal task(15 mins), ACE questionnaire(15 mins), totaling 95minutes for the entire interview

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • 1.Participants of any gender, above the age of 18 who can provide informed consent and are actively/willing to participate in the assessment procedures 2.Intentional Self-Harm/suicide attempts in the last 2 weeks.
  • 3.Participants who can read and write in Kannada/English.

排除标准

  • 1.Cognitive Impairment 2.Inability to cooperate with the interview.

结局指标

主要结局

Columbia-Suicide Severity Rating Scale(CSSRS)

时间窗: Baseline

Barratt Impulsiveness Scale (BIS-11)

时间窗: Baseline

Stop signal task(SST)

时间窗: Baseline

次要结局

  • Adverse Childhood Experiences (ACE) Questionnaire(Baseline)

研究者

申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Rajvi Amlani

Kasturba Medical college, Manipal, Udupi

研究点 (1)

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