Pilot study to evaluate the potential of growing out tumor infiltrating lymphocytes from cervical carcinoma
Recruiting
- Conditions
- Cervical carcinoma10038594
- Registration Number
- NL-OMON53901
- Lead Sponsor
- Antoni van Leeuwenhoek Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
• Histologically proven cervical carcinoma of at least FIGO 2018 stage IB1
• Age above 18 years
• Patients must have an indication for routine investigation or treatment under
general anesthesia during which tumor material can be obtained
• Able to provide written informed consent
Exclusion Criteria
• History of bleeding disorders
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>• To collect malignant (primary tumor or metastases) tissue from patients with<br /><br>cervical carcinoma.<br /><br>• To set up a TIL culture protocol for cervical carcinoma, resulting in a TIL<br /><br>product with sufficient cell numbers for adoptive T cell therapy<br /><br>• To evaluate potency of the TIL product through reactivity assays </p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>