Hypertension and the risk of developing cancer: a systematic review and meta-analysis
- Conditions
- Hypertension
- Registration Number
- JPRN-UMIN000052285
- Lead Sponsor
- Yokohama City University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Not provided
We will examine whether cancer risk is higher in people with hypertension. Drug use and cancer risk, such as antihypertensive medications, will be excluded. The search will be limited to solid tumors because blood cancers are rare in this topic. In addition, the following items will be used as exclusion criteria. (1) Systematic review or meta-analysis articles. (2) Case reports or case series reporting less than 50 cases. (3) The republished research literature is excluded unless the research includes new findings related to malignancy outcomes. (4) Studies published in languages other than English.
Study & Design
- Study Type
- Others,meta-analysis etc
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint is the risk of developing solid tumors in hypertensive patients. Odds ratios (ORs) will be calculated for the incidence of solid tumors in hypertensive patients and normotensive patients.
- Secondary Outcome Measures
Name Time Method The secondary endpoint is the risk of developing solid tumors in untreated hypertensive patients.