Usefulness of Exhaled NO in the Differential Diagnosis Acute Eosinophilic Pneumonia and Bacterial Pneumonia

• Conditions: Acute; Eosinophilic Pneumonia

• Registration Number: NCT01152424
• Lead Sponsor: Seoul National University Bundang Hospital

Brief Summary

Acute eosinophilic pneumonia (AEP) is diagnosed by cell count analysis of bronchoalveolar lavage fluid. However, the performance of bronchoscopy is not easy for patients with AEP, because they usually have hypoxia. Exhaled nitric oxide (FeNO) is usually elevated in the patients with eosinophilic inflammation such as asthma, but there is no previous studies FeNO in the patients with AEP. Investigators hypothesized that FeNO elevated significantly in patients with AEP, and FeNO can be used as non-invasive diagnostic method in patients who are clinically suspected with AEP, especially when the performance of bronchoscopy is difficult.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2010-06-24
• Study First Submitted QC: 2010-06-28
• Study First Posted: 2010-06-29
• Study Start: 2010-07
• Primary Completion: 2011-04
• Status Verified: 2011-06
• Last Update Submitted: 2011-06-07
• Last Update Posted: 2011-06-08
• Study Completion: 2011-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• All patients who visited the study hospital with bilateral pneumonic infiltration.

Exclusion Criteria

• Patients who do not agree with our study protocol

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The difference of FeNO in AEP and Community Acquired Pneumonia	Six months

Trial Locations

Locations (1)

Armed Forces Capital Hospital; 🇰🇷 Seongnam, Gyeongi, Korea, Republic of