Evaluating the Reproducibility of 3.0 Tesla MRI Continuous Arterial spin labeling in the Assessment of Cerebral Perfusio

Conditions: blood flow
cerebral blood flow
10007963

Registration Number: NL-OMON32170

Lead Sponsor: Academisch Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 10

Inclusion Criteria

healthy volunteers aged between 20 and 35

Exclusion Criteria

The presence of metal in the body (e.g. osteosynthetic material, pacemaker, artificial cardiac valves); claustrophobia; surgery performed in the area of measurement; known or symptomatic brain disease.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Cerebral Blood Flow (ml per 100 grams of brain tissue per minute) </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Cerebral Blood Flow (ml per 100 grams of brain tissue per minute) (mean whole<br /><br>brain Cerebral Blood Flow; mean Cerebral Blood Flow men and women; mean<br /><br>Cerebral Blood Flow left and right hemisphere)<br /><br><br /><br>Repeatability indices for CASL measurement of cerebral blood flow<br /><br><br /><br>Intraclass Correlation Coefficient for repeated measurements<br /><br><br /><br>Standard deviation of the paired difference between repeated measurements<br /><br><br /><br>Convergence of the difference of successive CASL measurements of cerebral blood<br /><br>flow when reducing the amount of acquisition averages. </p><br>