NCT00363441WithdrawnPhase 2
A Randomized Phase II Study of Conventional 3D Radiation (3DCRT) Versus Intensity-Modulated Radiation (IMRT) in Squamous Cell Cancer of the Head and Neck (SCCHN): Pilot Feasibility Study
Conditions
Trial Snapshot
- Phase
- Phase 2
- Status
- Withdrawn
- Sponsor
- Alberta Health services
- Primary Endpoint
- Prevalence and severity of side effects according to Radiation Therapy Oncology Group
Study Overview
Brief Summary
This is a randomized study of conventional 3d radiation versus intensity-modulated radiation in squamous cell cancer of the head and neck.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •histologically proven squamous cell carcinoma of the head and neck or squamous cell cancer to the neck from an unknown head and neck primary site, stage I-IV disease which is M0, age greater than 18 years, KPS greater than 70, signed study-specific consent
Exclusion Criteria
- •M1; bilateral N3 disease; primary greater than 10cm; salivary gland disease; life expectancy less than 2 years; prior radiotherapy to the head and neck; no signed study-specific consent form
Outcomes
Primary Outcomes
Prevalence and severity of side effects according to Radiation Therapy Oncology Group
scales and CTCAE version 3.0 for acute and chronic radiation toxicities, local control rates
Secondary Outcomes
No secondary outcomes reported
Investigators
Similar Trials
Unknown
Not Applicable
3D-Conformal Radiation vs Helical Tomotherapy in Prostate CancerProstate CancerNCT00326638Ottawa Hospital Research Institute72
Completed
Phase 3
Hypofractionated Image-Guided Radiation Therapy (IGRT) in Patients With Stage II-III Non-Small Cell Lung CancerNon-small Cell Lung CancerNCT01459497University of Texas Southwestern Medical Center103
Terminated
Not Applicable
3-Dimensional Conformal Radiation Therapy or Internal Radiation Therapy After Breast-Conserving Surgery in Treating Women With Stage I or Stage II Breast CancerBreast CancerNCT00802711Cancer Trials Ireland6
Completed
Phase 2
Intensity-Modulated Radiation Therapy and Paclitaxel With or Without Pazopanib Hydrochloride in Treating Patients With Anaplastic Thyroid CancerThyroid Gland Anaplastic CarcinomaNCT01236547National Cancer Institute (NCI)123
Unknown
Phase 3
Radiotherapy With or Without Concurrent Chemotherapy for Extensive Lymphatic Metastasis of Esophageal Cancer - 3JECROG P-03IMRT With or Without Concurrent Chemotherapy for Esophageal CancerNCT03328234Chinese Academy of Medical Sciences2