A comparative study of the effect of mouthwashes containing tranexamic acid and nanotrangasemic acid in leukemia patients
Phase 3
Recruiting
- Conditions
- Spontaneous oral bleeding in leukemia patients.Leukemia of unspecified cell type
- Registration Number
- IRCT20230104057046N2
- Lead Sponsor
- Gorgan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
Leukemia patients with oral bleeding
Patients diagnosed with thrombocytopenia (platelet count less than 20,000 units)
Selection of patients with the same frequency of use as assigned random classification
Selection of patients with the same interval of chemotherapy
Exclusion Criteria
Use of any anti-coagulant or anti-coagulant drugs (such as ASA, NSAID, ...) in the last month
Pregnant or nursing mothers
Hypersensitivity to tranexamic acid
Use of birth control pills
Smokers
Presence of severe periodontitis
The presence of diseases that prohibit the use of anticoagulants
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of times of spontaneous oral bleeding? the presence of spontaneous oral bleeding? the number of bleeding interdental areas after using an interdental toothbrush by the researcher. Timepoint: Measuring the number of bleeding interdental areas before the start of the intervention and 14 days after the start of the intervention? Measuring the number of bleeding times before and after using mouthwash (every day up to two weeks)? Identifying the presence of oral bleeding before and after using mouthwash (every day up to two weeks ). Method of measurement: Evaluation of the presence of bleeding by questionnaire - Evaluation of the number of bleeding areas by the researcher through interdental toothbrushes - Evaluation of the number of bleeding times by questionnaire.
- Secondary Outcome Measures
Name Time Method