MRI 3D UTE Hyper-Cones & ZTE for PET/MR Lung Attenuation Correction & for Lung Diagnostic Imaging
- Conditions
- Lung Diseases
- Interventions
- Diagnostic Test: PET/MR image acquisition
- Registration Number
- NCT03562806
- Lead Sponsor
- University of Zurich
- Brief Summary
MRI 3D UTE Hyper-Cones \& ZTE for PET/MR lung attenuation correction \& for lung diagnostic imaging
- Detailed Description
The primary objective is to clinically test the feasibility of 3D UTE Hyper-Cones \& ZTE in capturing lung density of patients with lung diseases at reasonable clinical imaging times compared to standard MR lung protocols (LAVA-Flex, PROPELLER). Secondly, we want to investigate if Hyper-Cones \& ZTE can be used for lung imaging such as vessels and air-pathways, oncological patients, lung nodules and lung infiltration \& parenchyma pathophysiology such as chronic obstructive pulmonary disease.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 9
- informed consent and signature
- clinical PET/CT planned and performed at Wagi site in Schlieren
- male or female patients
- from 18 to 80 years of age.
- same exclusion criteria as for the clinical PET/CT exam (i.e. pregnant women).
Additional exclusion criteria:
- standard exclusion criteria for clinical MRI (evaluated by clinical standard determined by MRI questionnaire).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description PET/MR (single arm) PET/MR image acquisition PET and MR sequence acquisition on SIGNA PET/MR device
- Primary Outcome Measures
Name Time Method Confirm that lung density map extraction is feasible through Hyper-Cones & ZTE scanning. 1 year Confirm that lung density map extraction is feasible through Hyper-Cones \& ZTE scanning.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Zurich, Department of Nuclear Medicine
🇨ðŸ‡Zurich, Switzerland