Photo-therapy With a Topical Retinoid Versus Photo-therapy Alone for Actinic Keratoses
Not Applicable
Withdrawn
- Conditions
- Actinic Keratoses
- Interventions
- Procedure: Photodynamic Therapy (PDT)Procedure: Topical retinoid and blue-light therapy with photosensitizing agent
- Registration Number
- NCT00756288
- Lead Sponsor
- Northwestern University
- Brief Summary
Evaluating safety and efficacy of the use of topical retinoid with photodynamic therapy for the treatment of actinic keratoses.
- Detailed Description
Evaluating safety and efficacy of the use of topical retinoid with photodynamic therapy vs photodynamic therapy alone for the treatment of actinic keratoses.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 2 Photodynamic Therapy (PDT) Light therapy with photosensitizing agent 1 Topical retinoid and blue-light therapy with photosensitizing agent Topical retinoid and Light therapy with photosensitizing agent
- Primary Outcome Measures
Name Time Method Live blinded rater and blinded photo rater analysis of areas at week 0 and week 6 for erythema, edema, crusting, ulceration, palpability, need to cease/delay treatment, and overall response in reduction of number of actinic keratoses (AKs). 6 weeks
- Secondary Outcome Measures
Name Time Method Subjects will assess pain, burning and itching on a scale of 0-3 at week 0, during retinoid treatment, during photo-therapy, one day after, and week 6. Also, principal investigator will evaluate adverse events at week 6. 6 weeks