NCT03121573已完成不适用
Efficacy and Safety of Duloxetine Among Individuals With Depressive Disorder in a 12 Weeks Trial
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 主要终点
- Change in Depression severity
研究概览
简要总结
The aim of this study was to investigate the effects of duloxetine on improvement of brain cortical activity in patients suffering from major depressive disorder using near infrared spectroscopy.
研究设计
- 研究类型
- Interventional
- 干预模型
- Sequential
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •HAMD-17 more than 12 points
- •Participants could understand this study and sign permit
- •Participants could receive NIRS measurements
- •Participants could comply with the protocol of the study
排除标准
- •alcohol or substance abuse within 3 months of the study
- •ever participate other clinical study related to duloxetine
- •previous poor treatment effects of duloxetine
- •concomitant use of MAOi within 14 days
- •concomitant use of Linezolid
- •with uncontrolled glaucoma
研究组 & 干预措施
intervention
Other
medication: duloxetine 30 to 60 mg tablets by mouth, QD to BID.
干预措施: Duloxetine (Drug)
结局指标
主要结局
Change in Depression severity
时间窗: 0-2-4-8-12 weeks
Hamilton Rating Scale for Depression
次要结局
- Change in Brain cortical activity(0-2-4-8-12 weeks)
研究者
相似试验
已完成
3 期
Efficacy and Safety of DuloxetineUrinary Stress IncontinenceNCT00190619Eli Lilly and Company100
Unknown
不适用
Tackling the effect of duloxetine on brain function in mood specific emotional processing in healthy volunteers: An fMRI study bridging pharmacotherapeutical and cognitive psychological approaches to depressioNL-OMON24781Radboud University Nijmegen Medical Centre24
已完成
3 期
A Study of Duloxetine in Adolescents With Juvenile Primary Fibromyalgia SyndromeFibromyalgiaNCT01237587Eli Lilly and Company184
已完成
4 期
Functional Change and Efficacy of Duloxetine in Patients With Co-Morbid Depression & Soft Tissue Discomfort SyndromeSoft Tissue Discomfort SyndromePainMajor Depressive DisorderNCT01035073University of Pennsylvania22
已完成
2 期
Pilot Study of Duloxetine in Adult Attention Deficit Hyperactivity Disorder(ADHD)Attention Deficit Disorder With HyperactivityNCT00940693Université de Montréal40