Development and evaluation of interventions in people with subjective cognitive decline

niversity of Bristol0 sites90 target enrollmentFebruary 21, 2019

Overview

No summary available.

Registry

who.int

Start Date

February 21, 2019

End Date

September 1, 2019

Last Updated

7 years ago

Study Type

Interventional

Sex

All

Sponsor

niversity of Bristol

•1\. Has expressed concern about cognitive decline (subjective cognitive decline) and has answered yes” to the following question: Are you concerned or worried that you are experiencing significant decline in your thinking abilities, more than just normal ageing?”
•2\. Aged over 45 years
•3\. In the opinion of the investigator, is capable of understanding and complying with protocol requirements
•4\. In the opinion of the investigator, is able to physically perform the cognitive tests and is fluent in the language that tests will be administered.
•The study also includes a small sample of people with Functional Cognitive Disorder (FCD). These patients are recruited through our Memory Clinic and have already received this diagnosis.

•1\. Has a current diagnosis or history of any type of cognitive impairment or dementia, or has a current diagnosis of neurological/psychiatric disorder or any other diagnosis that significantly affects cognitive performance (including substance abuse)
•2\. Incapable of doing a brisk walk
•3\. Has been exposed to the cognitive tests performed in this study within 6 months prior to the baseline assessment
•4\. Score on MoCA test is \<20\. An individual with a MoCA score this low may have significant cognitive decline (Larner, 2012\) and should be referred to their GP.
•5\. Knows his or her own ApoE genotype/phenotype
•6\. Cannot adequately understand verbal explanations or written information given in English