Assessment of Anti-aging Efficacy of Marine Collagen Peptides

Not Applicable

Recruiting

• Conditions: Skin Condition; Hair Fragility; Nails, Ingrown
• Interventions: Dietary Supplement: placebo drink; Dietary Supplement: Marine Collagen Peptides

• Registration Number: NCT06306105
• Lead Sponsor: TCI Co., Ltd.

Brief Summary

To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-03
• Study Start: 2024-03-04
• Study First Submitted: 2024-03-05
• Study First Submitted QC: 2024-03-05
• Study First Posted: 2024-03-12
• Last Update Submitted: 2024-03-15
• Last Update Posted: 2024-03-19
• Primary Completion: 2024-10-31
• Study Completion: 2024-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Healthy adults aged above 18 years old

Exclusion Criteria

• Subjects who are not volunteers
• Subjects who have been diagnosed with dermatitis, cirrhosis, and chronic kidney failure
• Subjects who have known cosmetic, drug or food allergies.
• Patients are taking medicine for chronic diseases
• Subjects receiving treaments for scalp, hair transplant, and other scalp medical care in past 12 weeks.
• Subjects getting a manicure and perm in past 12 weeks.
• Female who is pregnant or nursing or planning to become pregnant during the course of the study.
• Subjects receiving facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 12 weeks.
• Students who are currently taking courses taught by the principal investigator of this trial.
• Subjects are not willing to reveal the results of pictures after taking the product
• Vegetarian.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
placebo drink	placebo drink	-
Marine Collagen Peptides drinks	Marine Collagen Peptides	-

Primary Outcome Measures

Name	Time	Method
The change of skin hydation	Change from Baseline skin skin hydation at 12 weeks	Corneometer® CM825 (CK, Germany) was utilized to measure skin surface hydation. Units: arbitrary Corneometer® units 0-120.
The change of skin wrinkles	Change from Baseline skin wrinkles at 12 weeks	VISIA Complexion Analysis was utilized to measure skin wrinkles. Units: the amount of detectable wrinkles
The change of skin elasticity	Change from Baseline skin elasticity at 12 weeks	Cutometer® MPA580 was utilized to measure skin elasticity. Units: visco-elasticity in %.
The change of skin collagen density	Change from Baseline skin collagen density at 12 weeks	DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units
The change of thumbs nail color	Change from Baseline thumbs nail color at 12 weeks	Chroma Meter MM500 was utilized to measure thumbs nail color. Units: L\* index
The degree of nails fragility	Change from Baseline nails fragility at 12 weeks	Iron ruler was utilized to evaluate nails fragility. Picture taken was utilized to record and observe the change of nails fragility.
The change of hair follicle strength	Change from Baseline hair follicle strength at 12 weeks	Pull up the hair of the frontal bone, temporal bone and occipital bone (approximately 60 hairs/area) to assess the number of hair loss in each area. Units: the number of loss hair
The change of hair loss amount	Change from Baseline hair loss amount at 12 weeks	Collect and measure the weight of loss hair. Units: gram
The change of hair density	Change from Baseline hair density at 12 weeks	Soft Plus was utilized to picture and observe hair density.
The change of hair diameters	Change from Baseline hair diameters at 12 weeks	Mitutoyo C/N293-100 was utilized to measure hair diameters. Units: millimeter
The change of hair roots diameters	Change from Baseline hair roots diameters at 12 weeks	Mitutoyo C/N293-100 was utilized to measure hair roots diameters. Units: millimeter
The change of nails appearence	Change from Baseline nails appearence at 12 weeks	Picture taken was utilized to record and observe nails appearence.
The change of nails growth	Change from Baseline marking position at 12 weeks	Marking the position of middle fingers lunula was utilized to record and observe nails growth. Units: milimeter

Secondary Outcome Measures

Name	Time	Method
The change of self-assessment skin, hair, and nails condition	Change from Baseline skin, hair, and nails condition at 12 weeks	A self-assessment questionnaire was collected and evaluate skin, hair, and nails condition

Trial Locations

Locations (1)

Chia Nan University of Pharmacy & Science; 🇨🇳 Pingtung, Taiwan