Screening of Oral Human Papillomavirus (HPV)
Not Applicable
- Conditions
- Health Condition 1: B977- Papillomavirus as the cause of diseases classified elsewhere
- Registration Number
- CTRI/2024/04/064991
- Lead Sponsor
- Manipal Institute of Virology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
I. Patients above the age of 18 years with class III/IV oral cancer
II. Patients who have to undergo surgery for the removal of tumors
III. Patients complying to provide consent for the study.
Exclusion Criteria
I. Oral cancer patients not undergoing surgery for removal of tumors
II. Patients not willing to give consent for the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To assess the oral HPV prevalence among OSCC patients. This is crucial for devising appropriate strategies and for identifying highrisk groups that require targeted interventions. <br/ ><br>2. Study will help in the identification of other high-risk HPV among OSCC patients. <br/ ><br>3. The study will also explore saliva testing as a strategy for testing oral HPV among cancer population <br/ ><br>4. The study is also aimed to identify the impact of different risk factors associated with OSCC. <br/ ><br>5. Study will provide insights regarding mutational status of E6 and E7 oncogenes. <br/ ><br>Timepoint: 6 Months
- Secondary Outcome Measures
Name Time Method 4. The study is also aimed to identify the impact of different risk factors associated with OSCC. <br/ ><br>5. Study will provide insights regarding mutational status of E6 and E7 oncogenes. <br/ ><br>Timepoint: 12 Months