Analysis of Volatile Organic Compounds by Electronic Noses in Hospitalised Patients for an Infection by (SARS-CoV-2): Predictive Interest in Short-term Evolution
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Hopital Foch
- 入组人数
- 65
- 试验地点
- 1
- 主要终点
- Profiles of volatile organic compounds (VOCs) in exhaled air between 2 health conditions
研究概览
简要总结
The study of volatile organic compounds (VOCs) detected in exhaled air is an innovative research area for respiratory diseases. This analysis can be done by the technique of electronic nose, simpler and faster, which provides an idea of the general profile of the VOCs without identifying them. The VOCs in exhaled air in patients hospitalized for COVID-19 infection are analysed in this study, using electronic noses.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients infected by SARS-CoV-2 whose medical condition warrants hospitalisation (out of intensive care) for oxygen therapy less or equal to 4 l/min
- •Patients must be 18 years of age or older
- •Fluent in the French language
- •Have signed a consent form
- •Being affiliated with healthcare insurance
排除标准
- •Pregnant woman
- •Patient deprived of liberty by judicial or administrative decision
结局指标
主要结局
Profiles of volatile organic compounds (VOCs) in exhaled air between 2 health conditions
时间窗: 1 day
Comparison of variation of profiles of Volatile Organic Compounds in exhaled air from electronic noses (a set of sensors interacting with the VOCs exhaled). The analysis of the generated signal (resistance or load variations) is characteristic of the composition of VOCs), between patients who improve and patients who get worse during their hospitalisation for COVID-19 infection
次要结局
- Profiles of volatile organic compounds (VOCs) in exhaled air between 2 periods(4 months)
- Profiles of volatile organic compounds (VOCs) in exhaled air on 1 health condition(2 weeks)
- Profiles of volatile organic compounds (VOCs) in exhaled air by mass spectrometry at each visit based on patient evolution status.(4 months)