Analysis of Volatile Organic Compounds by Electronic Noses in Hospitalised Patients for an Infection by (SARS-CoV-2): Predictive Interest in Short-term Evolution
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- COVID-19
- Sponsor
- Hopital Foch
- Enrollment
- 65
- Locations
- 1
- Primary Endpoint
- Profiles of volatile organic compounds (VOCs) in exhaled air between 2 health conditions
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The study of volatile organic compounds (VOCs) detected in exhaled air is an innovative research area for respiratory diseases. This analysis can be done by the technique of electronic nose, simpler and faster, which provides an idea of the general profile of the VOCs without identifying them. The VOCs in exhaled air in patients hospitalized for COVID-19 infection are analysed in this study, using electronic noses.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients infected by SARS-CoV-2 whose medical condition warrants hospitalisation (out of intensive care) for oxygen therapy less or equal to 4 l/min
- •Patients must be 18 years of age or older
- •Fluent in the French language
- •Have signed a consent form
- •Being affiliated with healthcare insurance
Exclusion Criteria
- •Pregnant woman
- •Patient deprived of liberty by judicial or administrative decision
Outcomes
Primary Outcomes
Profiles of volatile organic compounds (VOCs) in exhaled air between 2 health conditions
Time Frame: 1 day
Comparison of variation of profiles of Volatile Organic Compounds in exhaled air from electronic noses (a set of sensors interacting with the VOCs exhaled). The analysis of the generated signal (resistance or load variations) is characteristic of the composition of VOCs), between patients who improve and patients who get worse during their hospitalisation for COVID-19 infection
Secondary Outcomes
- Profiles of volatile organic compounds (VOCs) in exhaled air between 2 periods(4 months)
- Profiles of volatile organic compounds (VOCs) in exhaled air on 1 health condition(2 weeks)
- Profiles of volatile organic compounds (VOCs) in exhaled air by mass spectrometry at each visit based on patient evolution status.(4 months)