24-hour Ambulatory Blood Pressure Monitoring in Patients With Blood Pressure Above Thresholds in General Practice
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,067
- 试验地点
- 7
- 主要终点
- Prevalence of 24-hour hypertension
研究概览
简要总结
High blood pressure (HBP) is a major modifiable cardiovascular risk factor which prevalence is gradually increasing. Reducing blood pressure (BP) significantly decreases cardiovascular morbi-mortality. Nevertheless, BP control remains insufficient: only 51% of French patients using antihypertensive drugs achieve the BP control targets.
HBP is mostly diagnosed and managed in primary care. Nevertheless, office BP measurements are unreliable for BP control and poorer predict target organ damage. Ambulatory BP measurements are recommended for HBP diagnosis and follow-up. 24-hour ambulatory blood pressure monitoring (ABPM) is the most cost-effective strategy. Its superiority has been demonstrated for HBP diagnosis and cardiovascular prognosis.
In France, ABPM is poorly available and little studied in primary care. Therefore, the investigators conducted a regional prospective study to analyze the feasibility and benefits of ABPM among primary care hypertensive patients in daily practice.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Prevalence of 24-hour hypertension
时间窗: at the time of ABPM, up to 30 days after the inclusion consultation
Proportion of patients with 24-hour high blood pressure in ABPM (24-hour systolic/diastolic BP\> 130/80 mmHg) among the patients with primary care office measured BP≥ 140/90 mmHg
Prevalence of nocturnal hypertension
时间窗: at the time of ABPM, up to 30 days after the inclusion consultation
Proportion of patients with nocturnal high blood pressure in ABPM (nighttime systolic/diastolic BP\> 120/70 mmHg) among the patients with primary care office measured BP≥ 140/90 mmHg
Prevalence of diurnal hypertension
时间窗: at the time of ABPM, up to 30 days after the inclusion consultation
Proportion of patients with diurnal high blood pressure in ABPM (daytime systolic/diastolic BP\> 135/85 mmHg) among the patients with primary care office measured BP≥ 140/90 mmHg
Prevalence of white-coat hypertension
时间窗: at the time of ABPM, up to 30 days after the inclusion consultation
Proportion of patients with normotension in ABPM (daytime systolic/diastolic BP\< 135/85 mmHg AND/OR nighttime BP\< 120/70 mmHg AND/OR 24-hour BP\< 130/80 mmHg) among the patients with primary care office measured BP≥ 140/90 mmHg
次要结局
- Dipping(at the time of ABPM, up to 30 days after the inclusion consultation)
- ABPM acceptability(at the time of ABPM, up to 30 days after the inclusion consultation)
- ABPM side effects(at the time of ABPM, up to 30 days after the inclusion consultation)
- Deprivation among hypertensive patients(at the time of ABPM, up to 30 days after the inclusion consultation)
- ABPM validity(at the time of ABPM, up to 30 days after the inclusion consultation)
研究者
Dr Claire ZABAWA
University senior registrar
University of Burgundy