Laboratory Based Identification of Heat Stress Biomarkers and Effective Cooling Interventions
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 试验地点
- 1
研究概览
简要总结
Our study has two goals. The first goal is to find a blood test that can detect signs of strain from heat in the body ("a biomarker"). Second, the study team wants to identify types of devices that can help people cool down quickly.
By identifying biomarkers for heat strain, scientists can better track and treat the health effects of heat. The study team will identify such biomarkers by simulating, in a laboratory-based environment, the heat and physical work that real-world workers experience.
In addition, the study team plans to test two cooling technologies that might keep people cool during physical activity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-50
- •Able to communicate in English or Spanish
- •General good health
- •A lifestyle that includes regular patterns of modest exercise
- •Body weight over 80 pounds
排除标准
- •Cannot provide informed consent
- •Known history of cardiac arrhythmias or having a pacemaker
- •Difficulty swallowing pills
- •Planned upcoming X-ray tests or MRI
- •Known history of gastroparesis, diverticulosis or diverticulitis, or inflammatory bowel disease
- •Previous surgery on stomach or intestines (except for appendix or gallbladder)
- •Pregnancy
- •Self-reported cardiac, kidney, or pulmonary disease, or diabetes
- •Concurrent use of temperature- or inflammation-modulating medications such as steroids or non-steroidal anti-inflammatory drugs (NSAIDs)
- •Staff under the direct supervision of any project directors or employed in the laboratory of the study investigators
研究者
Julie Parsonnet
George DeForest Barnett Professor of Medicine, Emerita
Stanford University
