JPRN-UMIN000030742已完成未知
Efficacy and safety of ripasudil hydrochloride in glaucoma patients being treated by prostaglandin analogues, but their intraocular pressures are 15mmHg or under. - Efficacy and safety of ripasudil hydrochloride in glaucoma patients being treated by prostaglandin analogues, but their intraocular pressures are 15mmHg or under.
Yotsuya Shirato Ophthalmology Clinic0 个研究点目标入组 30 人开始时间: 2018年1月18日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
The treated eyes showed significant reduction in IOP at 1 and 3 months. In contrast, contralateral untreated eyes did not show IOP reduction. IOP reduction of - 20% and - 30% was achieved in 30% and 10% treated eyes, respectively. There were significant differences in IOP between the treated and contralateral untreated eyes at 1 and 3 months. Two patients experienced local adverse events but soon recovered by discontinuing ripasudil. Ripasudil could be used to enhance the outcome of FP monotherapy.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20years-old 至 75years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •Patients who fall into any of the following criteria are excluded from participating in the study. 1. Patients with a contraindicated condition to use the study drug 2. Patients who are breastfeeding, pregnant, or parturient 3. Patients whose best-corrected visual acuity is less than 0.5 4. Patients whose spherical equivalent is less than -0.9D or +0.9 or higher 5. Patients in whom the difference of spherical equivalent between both eyes is 3D or higher 6. Patients whose intraocular pressure can not be correctly measured by Goldmann applanation tonometer 7. Patients whose mydriasis is insufficient and in whom the observation of the optic nerve head is impossible 8. Patients with history of invasive eye surgery or laser treatment, except cataract surgery within 6 months 9. Patients with eye trauma 10. Patients with complication of retina disease which affect visual field 11. Patients with optic nerve disease or intracranial disease which affect visual field 12. Patients with other conditions that the investigator/researcher thinks inappropriate for the study
研究者
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