Cortisol dynamics and chronobiological disruptions in adolescent obesity: A cross-sectional analysis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Serum cortisol levels
研究概览
简要总结
This study investigates the relationship between adolescent obesity, serum cortisol dynamics, and chronobiological disruptions. Using a cross-sectional design, it focuses on adolescents aged 17–19 years to explore the association between obesity, sleep patterns, and cortisol levels. Anthropometric indices such as BMI and waist-hip ratio will assess obesity, while validated questionnaires will gather data on sleep quality and chronotype. Serum cortisol levels will be measured to evaluate hypothalamic-pituitary-adrenal (HPA) axis activity. Stratified sampling will be employed to recruit college students in Puducherry. The findings aim to elucidate hormonal and lifestyle factors contributing to obesity, supporting the development of targeted public health interventions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 17.00 Year(s) 至 19.00 Year(s)（—）
- 性别
- Female
入选标准
- •BMI ≥25 kg/m2 (As per the Asian guidelines) and waist-hip ratio (WHR) ≥0.8 Body fat percentage of ≥35% (calculated by the formula (1.20 x BMI) + (0.23 x Age) – 5.4) Undergraduate female students in the age group of 17 to 19 years.
排除标准
- •Diagnosed obesity due to known endocrine disorders Participants taking medications that may cause obesity will not be included in the study.
结局指标
主要结局
Serum cortisol levels
时间窗: Baseline
次要结局
- Body mass index, blood pressure, waist-hip ratio and body fat percentage(Baseline)
研究者
Dr Jayabharathi M
Mahatma Gandhi Medical College and Research Institute, SBV (Deemed to be-University)