Effect of Chronic Grape Extract Supplementation in Trained Cross-training Athletes: A Randomized, Triple-blinded, Placebo-Controlled Crossover Study
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Universidad de Granada
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Performance
Study Overview
Brief Summary
The aim of this study is to investigate the effect of cronic GSE intake in crosstraining may have a favorable impact on biochemical markers, recovery, and performance.
Detailed Description
Supplementation with certain antioxidant nutrients is a feasible strategy to accelerate recovery from fatigue and prevent exercise-induced oxidative damage. Grape seed extract (GSE) contains flavonoids such as proanthocyanidins, which are potent antioxidants with numerous health benefits. Therefore, optimizing the recovery process after training is essential for athletes engaged in strength and power sports who aim to enhance performance.
Thirty trained CrossFit athletes consumed grape seed extract or a placebo for one week. The training session consisted of a 12-minute strength block, a 13-minute metabolic conditioning (MetCon), and a final 15-minute MetCon. The Rating of Perceived Exertion (RPE), Gastrointestinal Distress Score (GDS), blood pressure and the Perceived Recovery Status scale (RPS) were administered at the beginning of the session and at the end of each segment of the CrossFit session. DOMS was assessed using a visual analog scale at 24 and 48 hours after the CrossFit session.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Other
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 35 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Age: 18-35 years.
- •Body mass index: 18.5-30 kg/m
- •Ability to understand the instructions, objectives, and study protocol.
- •Minimum of 3 years of experience in crosstraining, with at least 6 hours of weekly training over the past 3 months.
- •Resident on the island of Tenerife.
Exclusion Criteria
- •History of a significant adverse cardiovascular event, renal insufficiency, cirrhosis, eating disorder, weight control surgical intervention, or type 2 diabetes mellitus.
- •Any chronic pathology in which the intake of nutritional supplements, especially use of antioxidant supplements during the 4 weeks prior to the start of the study.
- •Any condition that, in the investigator's judgment, would impair the ability to participate in the study or represent a personal risk to the participant.
- •Use of medications that may affect the study results.
- •Unstable body weight for 3 months prior to the start of the study (> 4 kg loss or gain in weight).
- •Active tobacco abuse or illicit drug use, or history of treatment for alcohol abuse.
- •On a special diet or prescribed for other reasons (e.g., celiac disease).
Arms & Interventions
Placebo
Preparation of colorants, sweeteners, aromas, and acidulants
Intervention: Placebo (Dietary Supplement)
Grape seed extract
600 mg of Grape seed extract
Intervention: Grape Seed Extract (Dietary Supplement)
Outcomes
Primary Outcomes
Performance
Time Frame: 60 minutes
Deep squat test at 70% of repetition maximum
Performance
Time Frame: 48 hours
Performance measured through the countermovement jump
Secondary Outcomes
- Attention(60 minutes)
- Performance: Weight used in the crosstraining session(60 minutes)
- Performance: Time performed in the crosstraining session(60 minutes)
- Subjective fatigue throug the the RPE scale(60 minutes)
- Gastrointestinal distress(60 minutes)
- Biochemical parameters(48 hours)
- Recovery(60 minutes)
- Delayed-onset muscle soreness (DOMS)(24 hours)
- Capillar lactate levels(60 minutes)
- Heart rate(60 minutes)
- Blood pressure(60 minutes)
Investigators
Lucas Jurado-Fasoli
PhD
Universidad de Granada