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Clinical Trials/NCT04375488
NCT04375488
Completed
Not Applicable

Effect Of Postoperative Inspiratory Muscle Training And Strength Exercise Training On Functional Capacity, Quality of Life, Respiratory Functions, Respiratory Muscle Strength And Endurance in Bariatric Surgery Patients

Bezmialem Vakif University1 site in 1 country30 target enrollmentDecember 27, 2019
ConditionsObesity, Morbid

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Obesity, Morbid
Sponsor
Bezmialem Vakif University
Enrollment
30
Locations
1
Primary Endpoint
Quality of Life Scale Specific for Obese Persons
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The aim of the investigator's study is to investigate whether postoperative inspiratory muscle training and resistance exercise training has an effect on functional capacity, respiratory functions, respiratory muscle strength and endurance in patients undergoing bariatric surgery.

Detailed Description

Obesity is an important health problem that can affect the entire organ and system of the body, leading to various disorders and even death. The fact that BMI is over 40 kg / m2 is defined as morbid obesity. The most effective treatment step in morbid obesity is bariatric surgery. The impairment of inspiratory muscle function related to obesity is associated with increased lung elastic load, excessive lengthening in the abdominal muscles, and dissolution of the diaphragm, leading to inspiratory muscle weakness and insufficiency. The decrease in its endurance is explained by the decrease of glycogen synthase activity in skeletal muscles. It was found that there was less decrease in the inspiratory muscle training patients whose MIP values were measured before bariatric surgery compared to those who could not do MIP values after surgery. Respiratory functions due to obesity are impaired due to restrictive mass increase in chest wall, tendency to breathe in low lung volumes and the effect of fat distribution on pleural pressure. Total lung volume, expiratory reserve volume (ERV), reserve volume (RV), vital capacity (VC), functional residual capacity (FRC), FVC, and FEV1 values are low. After bariatric surgery, patients' muscle strength decreased. In particular, there was a decrease in muscle strength in quadriceps, hamstring, biceps, triceps. The decrease in muscle strength after surgery has been associated with a decrease in muscle mass. It was stated that patients who did not exercise after surgery lost 7.6 kg of muscle, which was 29.7% of the total lost body weight. Resistance exercises performed after bariatric surgery have a positive impact on patients' muscle strength and functional capacity. Obesity causes a decrease in functional capacity. Increased step width, reduced walking speed and step length are shown for the main reasons. Decreased inspiratory muscle strength in patients undergoing surgery causes weakness in peripheral muscles. This weakness in peripheral muscles also reduces the functional capacity of patients. Inspiratory muscle training studies increase the functional capacity.

Registry
clinicaltrials.gov
Start Date
December 27, 2019
End Date
June 18, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Having a body mass index (BMI) ≥40kg / m2 or
  • (BMI) ≥35kg/m2 and at least one concomitant disease associated with obesity
  • To participate regularly in treatment

Exclusion Criteria

  • Using assistive device while walking
  • Lung infection in the past 1 month
  • Chronic obstructive pulmonary disease (COPD)
  • Having an orthopedic, neurological disease that will prevent him/her from exercising
  • Uncontrollable hypertension
  • Pregnancy

Outcomes

Primary Outcomes

Quality of Life Scale Specific for Obese Persons

Time Frame: 3 months

Quality of Life

5 times sit to stand test

Time Frame: 3 months

Mobility Test

6 minutes walking test

Time Frame: 3 months

functional capacity test

FEV1/FVC

Time Frame: 3 months

Respiratory Function Test

maximum expiratory pressure (MEP)

Time Frame: 3 months

Respiratory Muscle Strength Test

Hand grip dynamometer

Time Frame: 3 months

Static Peripheral Muscle Strength Test

Forced Vital Capacity (FVC)

Time Frame: 3 months

Respiratory Function Test

Forced Expiratory Volume in 1 second (FEV1)

Time Frame: 3 months

Respiratory Function Test

Peak Expiratory Flow (PEF)

Time Frame: 3 months

Respiratory Function Test

Forced expiratory flow over the middle one half of the FVC (FEF25-75%)

Time Frame: 3 months

Respiratory Function Test

maximum inspiratory pressure (MIP)

Time Frame: 3 months

Respiratory Muscle Strength Test

Hand-held Dynamometer

Time Frame: 3 months

Dynamic Muscle Strength Test

Maximal Voluntary Ventilation

Time Frame: 3 months

Respiratory Muscle Endurance Test

Study Sites (1)

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