跳至主要内容
临床试验/NCT04375488
NCT04375488已完成不适用

Effect Of Postoperative Inspiratory Muscle Training And Strength Exercise Training On Functional Capacity, Quality of Life, Respiratory Functions, Respiratory Muscle Strength And Endurance in Bariatric Surgery Patients

Bezmialem Vakif University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2019年12月27日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
1
主要终点
Quality of Life Scale Specific for Obese Persons

研究概览

简要总结

The aim of the investigator's study is to investigate whether postoperative inspiratory muscle training and resistance exercise training has an effect on functional capacity, respiratory functions, respiratory muscle strength and endurance in patients undergoing bariatric surgery.

详细描述

Obesity is an important health problem that can affect the entire organ and system of the body, leading to various disorders and even death. The fact that BMI is over 40 kg / m2 is defined as morbid obesity. The most effective treatment step in morbid obesity is bariatric surgery.

The impairment of inspiratory muscle function related to obesity is associated with increased lung elastic load, excessive lengthening in the abdominal muscles, and dissolution of the diaphragm, leading to inspiratory muscle weakness and insufficiency. The decrease in its endurance is explained by the decrease of glycogen synthase activity in skeletal muscles. It was found that there was less decrease in the inspiratory muscle training patients whose MIP values were measured before bariatric surgery compared to those who could not do MIP values after surgery.

Respiratory functions due to obesity are impaired due to restrictive mass increase in chest wall, tendency to breathe in low lung volumes and the effect of fat distribution on pleural pressure. Total lung volume, expiratory reserve volume (ERV), reserve volume (RV), vital capacity (VC), functional residual capacity (FRC), FVC, and FEV1 values are low.

After bariatric surgery, patients' muscle strength decreased. In particular, there was a decrease in muscle strength in quadriceps, hamstring, biceps, triceps. The decrease in muscle strength after surgery has been associated with a decrease in muscle mass. It was stated that patients who did not exercise after surgery lost 7.6 kg of muscle, which was 29.7% of the total lost body weight. Resistance exercises performed after bariatric surgery have a positive impact on patients' muscle strength and functional capacity.

Obesity causes a decrease in functional capacity. Increased step width, reduced walking speed and step length are shown for the main reasons. Decreased inspiratory muscle strength in patients undergoing surgery causes weakness in peripheral muscles. This weakness in peripheral muscles also reduces the functional capacity of patients. Inspiratory muscle training studies increase the functional capacity.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Having a body mass index (BMI) ≥40kg / m2 or
  • (BMI) ≥35kg/m2 and at least one concomitant disease associated with obesity
  • To participate regularly in treatment

排除标准

  • Using assistive device while walking
  • Lung infection in the past 1 month
  • Chronic obstructive pulmonary disease (COPD)
  • Having an orthopedic, neurological disease that will prevent him/her from exercising
  • Uncontrollable hypertension
  • Pregnancy

结局指标

主要结局

Quality of Life Scale Specific for Obese Persons

时间窗: 3 months

Quality of Life

5 times sit to stand test

时间窗: 3 months

Mobility Test

6 minutes walking test

时间窗: 3 months

functional capacity test

FEV1/FVC

时间窗: 3 months

Respiratory Function Test

maximum expiratory pressure (MEP)

时间窗: 3 months

Respiratory Muscle Strength Test

Hand grip dynamometer

时间窗: 3 months

Static Peripheral Muscle Strength Test

Forced Vital Capacity (FVC)

时间窗: 3 months

Respiratory Function Test

Forced Expiratory Volume in 1 second (FEV1)

时间窗: 3 months

Respiratory Function Test

Peak Expiratory Flow (PEF)

时间窗: 3 months

Respiratory Function Test

Forced expiratory flow over the middle one half of the FVC (FEF25-75%)

时间窗: 3 months

Respiratory Function Test

maximum inspiratory pressure (MIP)

时间窗: 3 months

Respiratory Muscle Strength Test

Hand-held Dynamometer

时间窗: 3 months

Dynamic Muscle Strength Test

Maximal Voluntary Ventilation

时间窗: 3 months

Respiratory Muscle Endurance Test

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验