Implementation of a Depression Screening Intervention at a Transgender Health Clinic in Thailand

Not Applicable

Completed

• Conditions: Depressive Symptoms
• Interventions: Behavioral: Depression Screening Intervention

• Registration Number: NCT05323695
• Lead Sponsor: Thai Red Cross AIDS Research Centre

Brief Summary

The study aims to develop and implement a depression screening intervention into routine HIV and sexual health service provision at a transgender health clinic in Thailand, and to explore the facilitators, barriers, feasibility and acceptability of the screening implementation.

Detailed Description

The study will follow a mixed-methods approach that will incorporate quantitative and qualitative components. Aim 1 will involve the development and implementation of depression screening intervention at Tangerine Clinic. Aim 2 will involve semi-structured interviews with a purposive subset of participants who received the intervention and healthcare providers to explore the multilevel facilitators, barriers, feasibility and acceptability of the screening implementation. Aim 3 will evaluate the proportion of participants who are offered, accept, and receive the peer-led depression screening intervention, and the proportion who screen positive.

Study Timeline

• Study First Submitted: 2021-07-08
• Study Start: 2021-10-11
• Study First Submitted QC: 2022-04-07
• Study First Posted: 2022-04-12
• Primary Completion: 2023-02-15
• Study Completion: 2024-07-02
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-22
• Last Update Posted: 2024-11-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 317

Inclusion Criteria

1. Thai nationality
2. Transgender women ≥18 years
3. Attending the Tangerine Clinic for routine care visits during the intervention period.
4. Can be a new or returning clients.

Exclusion Criteria

1. Transgender women currently receiving care for a mental health diagnosis will be excluded from participating in this study.

Inclusion Criteria for healthcare providers:

1. Currently working at the Tangerine Clinic
2. Can be medical doctors, nurses, peer counselors and other members of the clinic management team involved in the routine delivery of HIV and health services to Transgender women.

Exclusion criteria for healthcare providers

1. Not willing to participate in this study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Depression Screening Intervention	Depression Screening Intervention	All eligible participants will be screened using the Patient Health Questionnaire-2 (PHQ-2) for depression. If screened positive, participants will be further screened with Patient Health Questionnaire-9 (PHQ-9).

Primary Outcome Measures

Name	Time	Method
Number of participants screening positive for depression	Day 1	Screening positive is defined as scoring 7 or greater on PHQ-9. The total possible score for PHQ-9 is 27, with 0-6 being minimum and indicating no depressive symptoms, 7-12 mild depression, 13-18 moderate depression, and 19-27 severe depression.
Intervention Acceptability: Participants' perspective of the intervention through focus group discussion	Day 1	Acceptability will be assessed qualitatively through post-intervention focus group discussion.
Intervention Feasibility: Number of intervention completed	Day 1	Feasibility will be measured by number of intervention completed. Point estimates of \>50% of participants completed is considered as the minimum criteria for feasibility.
Intervention Feasibility: Participants' perspective of the intervention through focus group discussion.	Day 1	Feasibility will be assessed qualitatively through post-intervention focus group discussion.
Intervention Acceptability: Number of participants who accepted intervention	Day 1	Acceptability will be measured by the number of clients who were offered and accepted the intervention.
Intervention Acceptability: Participants' perspective of the intervention through in-depth interviews	Day 1	Acceptability will be assessed qualitatively through post-intervention in-depth interviews.
Intervention Feasibility: Participants' perspective of the intervention through in-depth interviews	Day 1	Feasibility will be assessed qualitatively through post-intervention in-depth interviews.

Trial Locations

Locations (1)

Institute of HIV Research and Innovation; 🇹🇭 Pathum Wan, Bangkok, Thailand