Evaluation of the effects of prophylactic misoprostol with oxytocin for postpartum hemorrhage in women with preeclampsia

Phase 3

• Conditions: severe pre-eclampsia.; Severe pre-eclampsia, third trimester; O14.13

• Registration Number: IRCT20201022049108N1
• Lead Sponsor: Karaj University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 May 2022

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 128

Inclusion Criteria

ALL pregnant mothers with severe pre-eclampsia who referred to the Shahi Kamali educational center in the study period
Hospitalization for C-section
Gestational age over 35 weeks
Having a healthy and alive fetus
Cephalic fetus
A maximum of 2 previous cesarean sections
Complete removal of the placenta after cesarean section
The age of 18-45 years

Exclusion Criteria

Mothers with coagulation disorders
History of maternal blood disorders
Chronic hypertension
Placental adhesion such as placenta previa and ecrta
Placental abruption (overt and covert)
Complications or emergency during surgery
Eclampsia
Mild pre-eclampsia
Abnormal placenta
History of uterine rupture
High bleeding risk
Indication for hysterectomy or T

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bleeding volume with gauze counting. Timepoint: Immediately, 1 hour, and 4 hours after C-section. Method of measurement: gauze counting.;Hemoglobin and hematocrit changes. Timepoint: 24 hours after C-section. Method of measurement: Blood test.