NCT00669201Unknown不适用
Wrist Cartilage - High Resolution in Vivo MR T2 Mapping- a Feasibility Study
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- wrist bone cartilage thickness can be measured and stratification can be observed on T2 mapping with correlation to T2 mapping of the knee cartilage
研究概览
简要总结
Purpose:Evaluate the feasibility of T2 cartilage mapping on MRI of the wrist and correlate with T2 mapping of knee cartilage.
Study protocol: Phase 1. 10 healthy volunteers, Phase 2. 10 volunteers with osteoarthritis of the wrist, Phase 3. 50 patients for studies for routine MR of the wrist.
MRI protocol: 3 T unit((Signa EXITE HDx),T1, T2 and T2 mapping sequences on axial and coronal orientation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Phase 2: No age limit, known OA on pre-existing X-rays
- •Phase 3: No age limit, routine MRI of the wrist
排除标准
- •Phase 1, 2: wrist trauma/surgery
- •All phases: any contraindication for MR: eg metals, claustrophobia, etc.
结局指标
主要结局
wrist bone cartilage thickness can be measured and stratification can be observed on T2 mapping with correlation to T2 mapping of the knee cartilage
时间窗: Within MRI completion (20 minutes)
次要结局
未报告次要终点
研究者
研究点 (2)
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