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临床试验/NCT01488240
NCT01488240招募中不适用

The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

University of Manitoba2 个研究点 分布在 1 个国家目标入组 6 人开始时间: 2012年11月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
6
试验地点
2
主要终点
Scar Characteristics

研究概览

简要总结

The purpose of this study is to determine the effects (good or bad) of pulsed dye laser treatment in burn scar height, texture, redness and pliability in acute burn injury.

详细描述

While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has yet to be conclusively demonstrated. For this reason, our research group is proposing the commencement of two randomized controlled trial pilot studies assessing the effects of pulsed dye laser (PDL) on burn scars. The objectives of this project will be to determine the effectiveness of pulsed dye laser therapy on burn scar vascularity, pliability, height and texture. It has been hypothesized that the PDL works on acute injury to decrease scar formation, and the fractional laser works on scar that is quiescent to promote remodelling. Therefore the investigators are proposing to study both acute injury and late burn scars. This project will compare the effects of each laser type, and will either help support or refute the assertion that laser therapy can be used to improve burn scars.

Objectives:

To determine the benefit of pulsed dye laser treatment in improving burn scar height, texture, vascularity and pliability in acute burn injury.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • burn scar
  • living in Winnipeg
  • scar age one to 6 months
  • Fitzpatrick I-III skin type

排除标准

  • open wound
  • active infection
  • previous scar treatment with steroid injection or interferon
  • established disposition towards keloid scarring

研究组 & 干预措施

Proximal

Active Comparator

part of scar proximal to heart

干预措施: pulsed dye laser (Procedure)

Distal

Active Comparator

part of scar distal to heart

干预措施: pulsed dye laser (Procedure)

结局指标

主要结局

Scar Characteristics

时间窗: six months

Examine characteristics of scar

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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