Investigating a Model for Acute Ischemic Pain in Humans
Not Applicable
Completed
- Conditions
- Peripheral Arterial Disease
- Registration Number
- NCT02192242
- Lead Sponsor
- Ludwig-Maximilians - University of Munich
- Brief Summary
The pathophysiology of acute ischemic pain is not well established. The aim of the present study was to investigate acute ischemic pain in humans with a view to establish a scientific model to perform future studies. The investigators examined whether peripheral nerve damage and acute inflammation occur during short episodes of acute ischemia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 11
Inclusion Criteria
- patients over 40 years
- unilateral femoral-popliteal PAD, Fontaine grade II
Exclusion Criteria
- patients with pain at rest or other pain origin
- diabetic polyneuropathy
- deep vein thrombosis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Induce acute ischemic pain during treadmill exercise (less than 15 minutes) To induce acute ischemic pain, patients performed treadmill exercise until intolerable pain developed.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Munich, Pettenkoferstr. 8a
🇩🇪Munich, Germany
University Hospital Munich, Pettenkoferstr. 8a🇩🇪Munich, Germany