Investigating a Model for Acute Ischemic Pain in Humans
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 1
- 主要终点
- Induce acute ischemic pain
研究概览
简要总结
The pathophysiology of acute ischemic pain is not well established. The aim of the present study was to investigate acute ischemic pain in humans with a view to establish a scientific model to perform future studies. The investigators examined whether peripheral nerve damage and acute inflammation occur during short episodes of acute ischemia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients over 40 years
- •unilateral femoral-popliteal PAD, Fontaine grade II
排除标准
- •patients with pain at rest or other pain origin
- •diabetic polyneuropathy
- •deep vein thrombosis
研究组 & 干预措施
Acute ischemic pain
acute ischemic pain was induced by treadmill testing in all patients investigated
干预措施: acute ischemic pain (Other)
结局指标
主要结局
Induce acute ischemic pain
时间窗: during treadmill exercise (less than 15 minutes)
To induce acute ischemic pain, patients performed treadmill exercise until intolerable pain developed.
次要结局
未报告次要终点
研究者
Philip Lang
Attending physician, Assistant Professor of Anesthesiology
Ludwig-Maximilians - University of Munich