Evaluation of therapeutic and immunologic effects of Crocina in knee osteoarthritis patients: A randomized double-blind placebo-controlled trial

Bojnourd University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新: 2019年8月26日

适应症

试验速览

暂无简介。

•1) aged over 40 years
•2) Primary osteoarthritis
•3) Pain in more than half the days of the previous month during one of the following activities: walking, climbing and stairs, standing up or sleeping on the bed or mattress during the night
•4) Radiographic evidence of tibiafemoral or patellofemoral osteoarthritis
•5) A score of 40 from the WOMAC scale as a base
•6) No intra-articular injection of hyaluronic acid / glucocorticoid over the last six months
•7) The lack of a positive pregnancy test or pregnancy program during the study

•1) intolerance to the drug
•2) Do not take medicine properly
•3) Serious medical conditions that the patient can not regularly attend periodic visits include severe cardiovascular disease such as angina or heart attack, severe hypertension, recent stroke, insulin dependent diabetes, psychiatric disorders, kidney disease, liver disease, active concen , And anemia
•4) history of liver disease
•5) Inability to walk without a cane
•6) A history of autoimmune diseases such as rheumatoid arthritis
•7) Secondary osteoarthritis, for example, following a trauma

发起方

Bojnourd University of Medical Sciences