A randomized phase III study to evaluate the effectiveness of two different dosing regimens (high dose vs daily) of Prednisone for boys with Duchenne muscular dystrophy in improving muscle strength and function and minimising side effects.
Phase 3
Recruiting
- Conditions
- Duchenne muscular dystrophyMusculoskeletal - Other muscular and skeletal disorders
- Registration Number
- ACTRN12605000075684
- Lead Sponsor
- The Children's Hospital at Westmead
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
Diagnosis of Duchenne muscular dystrophy, ambulant, steroid naïve.
Exclusion Criteria
No exclusion criteria
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Muscle strength[Measured at the start of the trial, and then 1,3,6,9 and 12 months after starting the prednisone]
- Secondary Outcome Measures
Name Time Method Minimum side effects[]