Real-time Assessment of the Histology of Colorectal Polyps Using Electronic Chromoendoscopy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Colorectal Polyp
- Sponsor
- University of Erlangen-Nürnberg Medical School
- Enrollment
- 230
- Locations
- 1
- Primary Endpoint
- Accuracy of predicting histology with EC
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
To assess the accuracy of predicting histology of colorectal polyps with electronic chromoendoscopy.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients undergoing screening or surveillance colonoscopy
- •written informed consent
Exclusion Criteria
- •inadequate bowel preparation
- •polyposis syndromes
- •history of colectomy
- •use of anticoagulants
Outcomes
Primary Outcomes
Accuracy of predicting histology with EC
Time Frame: 1 year
Polyps will be visualized in white-light and the location and size will be noted. Afterwards, electronic chromoendoscopy will be used to visualize and enhance the mucosal vascular pattern and the mucosal surface pattern morphology of the polyp. The endoscopist will then make a real time assessment of each polyp according to size, shape, Paris classification and surface characteristics including pit pattern and mucosal vascular pattern morphology, colour, and type of depression. Further, a level of confidence (high or low) will be made for the real time histology prediction. Finally, all polyps will be removed using standard techniques and processed for pathological evaluation and real time and histological results will be compared.