Prevalence of Vitreomacular Adhesion in Patients 40 Years and Older
- Conditions
- Vitreomacular Adhesion
- Registration Number
- NCT02160340
- Lead Sponsor
- Nova Southeastern University
- Brief Summary
The purpose of this study is to evaluate the prevalence of vitreomacular adhesion (VMA) in patients 40 years and older using Spectral Domain Optical Coherence Tomography.
- Detailed Description
As a function of age, liquefaction of the vitreous body results in separation of the vitreous cavity from the retina. This posterior vitreous separation may be incomplete, leading to areas of residual VMA. These adhesions can result in maculopathies such as vitreomacular traction syndrome, macular hole, epiretinal membrane, cystoid macular edema, diabetic macular edema, neovascularization in diabetic retinopathy and retinal vein occlusion, exudative age-related macular degeneration, and myopic traction maculopathy. VMA may lead to pathological sequelae due to the static and dynamic anteroposterior tractional forces to the surface of the macula. The resultant complication will depend on the size and strength of the traction, with smaller areas of adhesion leading to greater traction. Identifying the prevalence of vitreomacular adhesion and its associated complications will yield valuable, new epidemiologic data, leading to improved diagnosis and management of patients with this condition. The prevalence of vitreomacular adhesion in specific age groups has not been investigated.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1584
40 years and older
- Clear media
Less than 40 years of age
- Prior history of vitreoretinal surgery or pharmacotherapy with intravitreal injection
- Dense media opacity
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method What is the overall prevalence of Vitreomacular adhesion in the population 40 years and older? Two years Prevalence will be measured using Spectral Domain Optical Coherence Tomography. Tomography scans will be evaluated for the presence or absence of vitreomacular adhesion.
- Secondary Outcome Measures
Name Time Method Is there is a significant correlation between VMA and various maculopathies including diabetic macular edema, retinal vascular occlusion, and age-related macular degeneration? 2 years Spectral domain optical coherence tomography scans will be used to evaluate for the presence of isolated or concomitant vitreomacular adhesion.
Trial Locations
- Locations (18)
Schaeffer Eye Center
🇺🇸Birmingham, Alabama, United States
Leo Semes
🇺🇸Birmingham, Alabama, United States
Schwartz Laser Eye Center
🇺🇸Scottsdale, Arizona, United States
VA Greater Los Angeles Healthcare System
🇺🇸Sepulveda, California, United States
Front Range Eye Associates
🇺🇸Broomfield, Colorado, United States
Aran Eye Associates
🇺🇸Coral Gables, Florida, United States
Nova Southeastern University
🇺🇸Fort Lauderdale, Florida, United States
Retina Macula Specialists of Miami
🇺🇸Miami, Florida, United States
Murray Ocular Oncology and Retina
🇺🇸Miami, Florida, United States
Vitreous and Retina Consultants
🇺🇸Winter Haven, Florida, United States
Scroll for more (8 remaining)Schaeffer Eye Center🇺🇸Birmingham, Alabama, United States